TABLE 3.

Plasma apoA-I concentrations in mg/dl across HDL subfractions as defined by size

	Normal Weight	Obese
	(n = 20)	(n = 20)	P
Very small	12 ± 7	17 ± 11	0.1
Small	60 ± 30	51 ± 15	0.1
Medium	22 ± 14	32 ± 18	0.03
Large	25 ± 18	17 ± 11	0.1

Means ± SD. Very small (discoidal) HDL, 66 kDa or smaller; small HDL, 66–140 kDa; medium HDL, 140–232 kDa; large HDL, 232–440 kDa. P values <0.05 were considered to indicate statistical significance for the difference between normal weight and obese groups as determined by MANOVA test of variables expressed as means ± SD. Overall MANOVA test for difference in apoA-I concentration of the four HDL sizes between normal weight and obese groups is significant, P = 0.007.