Table 1.
Sample | DP 30 min | DP 2 h | DE 30 min | DE 4 h | RDR 5 min |
---|---|---|---|---|---|
Pure MBZ | 21.82±4.32 | 41.95±1.69 | 10.31±1.53 | 38.38±1.77 | 1 |
Recrystallized MBZ | 17.42±4.55 | 42.02±3.32 | 7.94±1.94 | 37.22±3.38 | 0.7 |
RDM-1:1 | 25.20±2.27 | 52.80±3.02 | 12.99±1.17 | 47.60±2.65 | 1.4 |
RDM-1:2.5 | 54.84±2.55 | 78.86±2.69 | 35.77±1.18 | 71.90±1.77 | 4.0 |
RDM-1:5 | 50.47±1.50 | 71.88±1.32 | 32.79±1.27 | 64.88±1.16 | 4.0 |
Notes: DP at 30 min and 2 h; DE at 30 min and 4 h, and RDR at 5 min of MBZ raw material; recrystallized MBZ; RDM-1:1; RDM-1:2.5, and RDM-1:5.
Abbreviations: DE, dissolution efficiency; RDR, relative dissolution rate; h, hours; min, minutes; MBZ, mebendazole; RDM, redispersible microparticles.