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. 2014 Sep 18;8:1467–1479. doi: 10.2147/DDDT.S65561

Table 1.

Results of dissolution test expressed in terms of drug percent (DP), dissolution efficiency (DE) and relative dissolution rate (RDR)

Sample DP 30 min DP 2 h DE 30 min DE 4 h RDR 5 min
Pure MBZ 21.82±4.32 41.95±1.69 10.31±1.53 38.38±1.77 1
Recrystallized MBZ 17.42±4.55 42.02±3.32 7.94±1.94 37.22±3.38 0.7
RDM-1:1 25.20±2.27 52.80±3.02 12.99±1.17 47.60±2.65 1.4
RDM-1:2.5 54.84±2.55 78.86±2.69 35.77±1.18 71.90±1.77 4.0
RDM-1:5 50.47±1.50 71.88±1.32 32.79±1.27 64.88±1.16 4.0

Notes: DP at 30 min and 2 h; DE at 30 min and 4 h, and RDR at 5 min of MBZ raw material; recrystallized MBZ; RDM-1:1; RDM-1:2.5, and RDM-1:5.

Abbreviations: DE, dissolution efficiency; RDR, relative dissolution rate; h, hours; min, minutes; MBZ, mebendazole; RDM, redispersible microparticles.