Figure 8.

EGR1 expression in the whole accumbens corridor 2 h after cocaine CPP reacquisition correlates with time spent in the cocaine compartment. The correlation of EGR1 expression per mm² vs. the time spent in the cocaine compartment during the cocaine CPP reacquisition test is given for animals that had undergone cocaine conditioning and extinction with saline (COCAINE, red triangles, filled) and for animals that were counterconditioned with social interaction after an initial cocaine conditioning (SOCIAL, green circles, filled) and is shown as a continuous line. There was no statistically significant correlation (shown as a dashed line) between the EGR1 expression per mm² and the time spent in the cocaine compartment for animals injected noncontingently with cocaine (NONCONT; red triangles, unfilled).