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Collagen maturation as determined by Van Gieson’s staining. A higher number of red pixels/hpf is indicative of a higher density of mature collagen. At day 7, group A demonstrated a significantly greater density of mature collagen compared with all other groups. At day 10, group B showed a similar density of mature collagen relative to group A, and this area was significantly greater than that of groups C and D. *P < 0.05.
