Fig. 5.

The in vivo fluorescence imaging for blood flow network at a resolution of 85 μm with Pearl Impulse. A, In Allo-control group, vascular network is not visualized possibly due to thickened tissue or thrombosis of blood vessels as early as 2 days after rejection started. The blood flow was preserved; however, 2 days after start of rejection in the Allo-CsA group, corresponded to the slower rejection course observed in this treated group even after withdrawal of immunosuppressant. B, Macroscopic evidence of vessel outgrowth from the transplanted abdominal wall to surrounding recipient abdominal tissue was seen. Blue arrows denote the suture line and red arrow points to the outgrown blood vessel.