Table 1.
Descriptive preoperative characteristics of 253 patients treated with radical nephroureterectomy and ipsilateral bladder cuff for upper-tract urothelial carcinoma
| Variable | All patients (n = 253) |
Tumor location* |
||
|---|---|---|---|---|
| Renal pelvis (n = 171) |
Ureter (n = 78) |
p value | ||
| Median age, yr (IQR) | 72 (64-77) |
71 (63-78) | 73 (66-77) | 0.7 |
| Gender, No. (%) | ||||
| Male | 159 (63) | 104 (61) | 52 (67) | 0.4 |
| Female | 94 (37) | 67 (39) | 26 (33) | - |
| Race, No. (%) | ||||
| White | 233 (92) | 157 (92) | 72 (92) | 0.8 |
| Other | 20 (8) | 14 (8) | 6 (8) | - |
| ASA score, No. (%) | ||||
| 1 | 7 (3) | 4 (2) | 3 (4) | 0.8 |
| 2 | 126 (50) | 86 (50) | 39 (50) | - |
| 3 | 119 (47) | 80 (47) | 36 (46) | - |
| Smoking history, No. (%) | 186 (74) | 128 (75) | 54 (69) | 0.4 |
| Previous non-muscle-invasive bladder tumor, No. (%) |
86 (34) | 52 (30) | 31 (40) | 0.2 |
| Previous endoscopic tumor ablation, No. (%) |
20 (8) | 10 (6) | 6 (8) | 0.6 |
| Hematuria, No. (%) | ||||
| No | 63 (25) | 36 (21) | 27 (35) | 0.04 |
| Microhematuria | 28 (11) | 22 (13) | 5 (6) | - |
| Gross hematuria | 162 (64) | 113 (66) | 46 (59) | - |
| Positive void cytology, No. (%) | 191 (75) | 126 (74) | 64 (82) | 0.3 |
| Hydronephrosis on preoperative imaging, No. (%) |
125 (49) | 62 (36) | 62 (79) | <0.000 1 |
| Parenchymal/sinus fat extension or extraureter extension on imaging, No. (%) |
26 (10) | 30 (18) | 6 (8) | 0.05 |
| Suspicious nodes on imaging, No. (%) | 21 (8) | 16 (9) | 5 (6) | 0.6 |
| High-grade disease, No. (%)† | 181 (73) | 121 (71) | 58 (74) | 0.6 |
IQR = interquartile range; ASA = American Society of Anesthesiologists.
*
n = 4, pT0 patients (submitted to previous endoscopic tumor ablation).
†
Based on biopsy and wash/brush cytology.