Table 3.
Linear Regression Analysis of Circulating Cytokine Levels pg/mL (IFN-γ, TNF-α, IL-6, IL-1β, IL-4, and IL-10) and HbA1c% in Diabetes Type I Patients Living in Moderate Altitude Area Compared to Diabetes Type I Patients Living at Sea Level
| Unadjusted Ba95% CI | P value | Adjusted B (95% CI)b | P value | |
|---|---|---|---|---|
| IFN-γ | 9.13 (8.00–10.27) | <0.001 | 10.89 (9.54–12.23) | <0.001 |
| TNF-α | 11.89 (10.62–13.15) | <0.001 | 12.10 (10.78–13.43) | <0.001 |
| IL-6 | 14.81 (13.59–16.04) | <0.001 | 14.68 (13.40–15.98) | <0.001 |
| IL-10 | 10.13 (9.28–10.99) | <0.001 | 10.04 (9.15–10.94) | <0.001 |
| IL-4 | 15.68 (14.67–16.69) | <0.001 | 16.03 (14.99–17.07) | <0.001 |
| IL-1β | 5.44 (4.96–5.91) | <0.001 | 5.42 (4.92–5.92) | <0.001 |
| HbA1c% | 4.03 (3.71–4.36) | <0.001 | 4.00 (3.66–4.34) | <0.001 |
a
B represents unstandardized coefficients (the values for the regression equation for predicting the dependent variable from the independent variable) while CI represents confidence intervals. bB (95%CI) adjusted with sex and age.