Fig. 1.

Bendamustine or entinostat alone inhibits proliferation of MM cells in a dose-dependent manner. Human MM cells were plated onto 96-well plates with fresh RPMI1640 medium (0.5% FBS) or same medium containing indicated concentrations of bendamustine (Benda) or entinostat (Ent) for 72 h. The percentages of surviving cells as compared to controls, defined as 100% survival, were determined by reduction of MTS. Data shows the representative of three independent experiments. Bars, SD. (A) bendamustine; (B) entinostat.