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. Author manuscript; available in PMC: 2014 Sep 25.
Published in final edited form as: Cancer Lett. 2013 Feb 28;335(2):343–350. doi: 10.1016/j.canlet.2013.02.046

Fig. 2.

Fig. 2

Combination of bendamustine and entinostat significantly induces growth inhibition of MM cells, and is synergistic over a wide range of effects. (A) Human MM cells were plated onto 96-well plates with fresh RPMI1640 medium (0.5% FBS) or same medium containing indicated concentrations of bendamustine (Benda) or entinostat (Ent) or their combinations with a fixed ratio for 72 h. The percentages of surviving cells as compared to controls, defined as 100% survival, were determined by reduction of MTS. Data shows the representative of three independent experiments. Bars, SD. P values vs bendamustine single agent. (B) The combination index (CI) curves were calculated using Calcusyn software according to the Chou–Talalay equation.