Figure 5. Pro-angiogenic effects elicited by knockdown of miR-377 are largely dependent on VEGF.

In vitro Tube Formation Assay showed that total capillary tube lengths (A) and tube branch points (B) were significantly reduced by the VEGF siRNA transfection in miR-377-knockdown HUVECs. All values were expressed as means ± SE; n = 6 for each group; * P<0.05 was considered statistically significant.