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. 2014 Aug 1;7(10):1185–1191. doi: 10.1242/dmm.017079

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© 2014. Published by The Company of Biologists Ltd

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Fig. 4. — Absence of fetal growth restriction on the BL6 genetic background. (A) Fetal wet weights on the BL6 genetic background at E14.5, E16.5 and E18.5 for Phlda2^{+/+BACx1(BL6)} (2×), and at E18.5 for Phlda2^{+/+BACx3(BL6)} (4×). Fetuses were the same weight as their non-transgenic counterparts at each time point. (B) Placental wet weights on the BL6 genetic background at E14.5, E16.5 and E18.5 for Phlda2^{+/+BACx1(BL6)} (2×) and at E18.5 for Phlda2^{+/+BACx3(BL6)} (4×). Placentae were significantly lighter that non-transgenic placentae at each time point. (C) Fetal:placental (F:P) weight ratios. Ratios were significantly different compared with non-transgenic mice at each time point on the BL6 genetic background, but only at E14.5 and E16.5 on the 129 genetic background. Numerical data is given in supplementary material Table S4. NS, not significant (P>0.05), *P<0.05, **P<0.01, ***P<0.005.