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. 2014 Aug 1;7(10):1193–1203. doi: 10.1242/dmm.015859

Fig. 1.

Fig. 1.

Design and cargo release rate of nanoparticle constructs. (A) Cartoon of PLGA nanoparticle functionalised with avidin for binding of biotinylated targeting antibody. Cargo for delivery is embedded within the solid PLGA matrix. Cargo abbreviations of LIF, BDNF, GDNF, DHF and XAV are detailed in the main text; RA, retinoic acid. (B) Scanning electron micrograph of nanoparticles showing tight size distribution: average diameter is 120 nm. (C) Cargo release rate from PLGA nanoparticles (NP) as exemplified by LIF after suspending LIF-nano in aqueous medium and sampling using ELISA measurements.