Table 3. Type of recurrence and lymphovascular space invasion in stage I ovarian cancer.

		Hematogenous and lymphatic			Peritoneal
	No.	5-year (%)	HR (95% CI)	P-value	5-year (%)	HR (95% CI)	P-value
LVSI				0.002			0.29
No	358	3.2%	1		4.3%	1
Yes	76	16.2%	4.79 (1.75-13.2)		1.7%	0.33 (0.04-2.56)
Age				0.28			0.75
< 65	357	5.8%	1		4.0%	1
≥ 65	77	4.8%	0.33 (0.04-2.50)		2.8%	0.78 (0.17-3.67)
High-grade serous				0.20			0.086
No	398	4.8%	1		3.2%	1
Yes	36	12.0%	2.34 (0.63-8.64)		12.0%	3.26 (0.85-12.6)
Stage				1.0			0.05
IA	136	3.3%	1		0.9%	1
IB-C	298	6.8%	1.00 (0.27-3.68)		5.2%	8.20 (1.00-67.1)
Chemotherapy*				0.74			0.14
No	110	3.9%	1		4.3%	1
Yes	315	6.3%	0.78 (0.19-3.27)		3.8%	0.37 (0.10-1.36)

Multivariate analysis with Cox proportional hazard regression test (grade was not entered in the model due to 179 clear cell histology cases that had no grading).

^*postoperative chemotherapy.

Abbreviations: No., number; 5-year (%), 5-year cumulative rate; HR, hazard ratio; 95%CI, 95% confidence interval; and LVSI, lymphovascular space invasion.