Fig. 8.
Effects of mRFP-tagged dnPDE2A (catalytically dead mutant) on cell growth and invasion. Data in graphs are means of three independent experiments, each performed in triplicate. (A) Effects of mRFP-tagged dnPDE2A on cell growth. Cells were transfected with mRFP-tagged dnPDE2A, and, after 48 h, plated at 400 cells/well in a 96-well plate. The error bars represent means ± SD, n = 3. A significant treatment effect is noted (*, P < 0.01 compared with Mock treatment). (B) Effects of mRFP-tagged dnPDE2A on cell invasion. Cells were transfected with mRFP-tagged dnPDE2A, and cell invasion was examined after 16 h. The error bars represent means ± SD, n = 3. A significant treatment effect is noted (*, P < 0.01 compared with mock treatment).