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. Author manuscript; available in PMC: 2014 Sep 25.
Published in final edited form as: Mol Cancer Ther. 2011 Jul 11;10(9):1635–1643. doi: 10.1158/1535-7163.MCT-10-0887

Figure 5. siRNAs targeting ER stress pathway protect against CEMB-induced cytotoxicity.

Figure 5

PPC-1 cells were transfected with IRE1-α (A), PERK (B), ATF6 (C), or Ask1(D) siRNAs for 48 hours and then treated with CEMB (2 μM) or Thapsigargin (5 μM) for 24h. ATP levels were measured and data expressed as % relative to DMSO treated cells transfected with scrambled control siRNA (mean ± SEM; n=3).