Table 1.
Vδ | N | D1 | N | D2 | N | Jδ | Vγ | N | Jγ | ||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cy3 | NX6 | Vδ8 | C A A S | A | T D K | Vγ1 | C A V W | S R | S G T S W V K | ||||
C5 | Vδ6A | C A L W E L | G | G G I R | A S | D K | Vγ1 | C A V W | T R | G T S W V K | |||
NP | 1G9 | Vδ4 | C A L M E R | R | G Y | R R D T | R A | D K | Vγ4 | C S Y G S | Y | S S G F H K | |
1E3 | Vδ6B | C A L S E L | G G | G G | S A | T D K | Vγ1 | C A V W | K K T | G T S W V K | |||
1B2 | Vδ4 | C A L M E R | V | G | L Y | R R D T | S L A | T D K | Vγ1 | C A V | F | S G T S W V K |
Each pair of γ and δ chain sequences were identified from a single Cy3 or NP-specific γδ T cell derived from mouse splenocytes and verified by their ability to confer NP- or Cy3-specific binding to 58α-β- cells expressing the TCR.