Table 1.

Phenotype changes in PN21

A male	CON	IUGR	PNGR	IPGR
Body weight (g)	65.7 ± 1.7	64.3 ± 1.0	22.8 ± 0.7***	23.5 ± 0.7***
Plasma glucose (mM)	12.3 ± 1.3	9.60 ± 0.61*	7.61 ± 0.70**	7.82 ± 0.69**
CSF glucose (mM)	3.55 ± 0.28	3.25 ± 0.23	2.30 ± 0.15**	3.11 ± 0.25
Plasma lactate (mM)	2.47 ± 0.06	2.24 ± 0.33	2.73 ± 0.29	2.23 ± 0.27
CSF lactate (mM)	1.22 ± 0.05	1.10 ± 0.10	1.65 ± 0.23	1.34 ± 0.12
Plasma ketones (µM)	526 ± 46	658 ± 101	899 ± 64**	934 ± 60**
CSF ketones (µM)	182 ± 24	261 ± 57	615 ± 37*	506 ± 12*
B female	CON	IUGR	PNGR	IPGR
Body weight (g)	56.0 ± 0.9	59.8 ± 1.7*	22.7 ± 0.6***	22.3 ± 0.6***
Plasma glucose (mM)	11.4 ± 0.31	8.65 ± 0.19***	6.65 ± 0.21***	5.36 ± 0.19***
CSF glucose (mM)	3.84 ± 0.14	3.50 ± 0.13	2.81 ± 0.21***	2.84 ± 0.12***
Plasma lactate (mM)	0.762 ± 0.077	0.843 ± 0.051	0.783 ± 0.111	0.723 ± 0.080
CSF lactate (mM)	0.618 ± 0.067	0.698 ± 0.038	0.614 ± 0.126	0.624 ± 0.086
Plasma ketones (µM)	457 ± 80	544 ± 86	669 ± 56	560 ± 50
CSF ketones (µM)	191 ± 27	227 ± 36	514 ± 60***	485 ± 20***

Data are shown as means ± SE (n=5–6).

^*P<0.05;

^**P<0.01;

^***P<0.001 vs. CON by one-way ANOVA.