Table 2.

Phenotype changes in PN50

A male	CON	IUGR	PNGR	IPGR
Body weight (g)	276 ± 5	254 ± 5**	184 ± 1***	198 ± 4***
Plasma glucose (mM)	8.72 ± 0.32	7.74 ± 0.25	5.85 ± 0.23***	5.32 ± 0.64***
CSF glucose (mM)	3.29 ± 0.20	2.85 ± 0.13	2.15 ± 0.11***	2.04 ± 0.24***
Plasma lactate (mM)	1.16 ± 0.08	1.08 ± 0.07	0.906 ± 0.054*	0.947 ± 0.056
CSF lactate (mM)	1.23 ± 0.04	1.17 ± 0.06	1.05 ± 0.03**	1.15 ± 0.03
Plasma ketones (µM)	460 ± 69	381 ± 66	396 ± 41	302 ± 65
CSF ketones (µM)	271 ± 10	271 ± 6	433 ± 29*	413 ± 59
B female	CON	IUGR	PNGR	IPGR
Body weight (g)	168 ± 6	189 ± 5*	153 ± 3**	148 ± 4**
Plasma glucose (mM)	9.27 ± 0.59	8.90 ± 0.53	7.31 ± 0.94	9.74 ± 1.23
CSF glucose (mM)	2.75 ± 0.37	2.33 ± 0.11	2.92 ± 0.41	3.55 ± 0.47
Plasma lactate (mM)	1.97 ± 0.22	1.81 ± 0.17	1.26 ± 0.14**	1.39 ± 0.17
CSF lactate (mM)	1.54 ± 0.06	1.52 ± 0.07	1.35 ± 0.07	1.23 ± 0.03*
Plasma ketones (µM)	688 ± 38	766 ± 45	647 ± 75	456 ± 134
CSF ketones (µM)	149 ± 28	180 ± 17	124 ± 18	91.1 ± 32.9

Data are shown as means ± SE (n=5–6).

^*P<0.05;

^**P<0.01;

^***P<0.001 vs. CON by one-way ANOVA.