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. 2014 Sep 25;5:363. doi: 10.3389/fphys.2014.00363

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Copyright © 2014 Lovett, Chu, Wang, Ratcliffe and Baker.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Pooled data of Hill parameters derived from fitting the force-Ca²⁺ relationship for individual experiments to the Hill equation. (A) F_max (maximum Ca²⁺-activated force). (B) Ca²⁺ sensitivity EC₅₀ ([Ca²⁺] at 50% Fmax). (C) Hill coefficient n_H (slope of Ca²⁺-force relationship at EC₅₀). For all Hill parameters, no statistical differences were found between NTT-MMP-2 vs. wild type (P ns, Two-Way ANOVA; mean ± SE, n = 4/group).