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. 2014 Sep 25;6:259. doi: 10.3389/fnagi.2014.00259

Table 2.

The association of brain volumes with fine motor skills.

n = 1,126 Clinical score Length of drawing (cm) Movement time (s) Speed variability (cm/s) Deviation from template (cm2) Number of crossings template
Cerebral gray mattera 0.06 (0.10;0.02) −0.09 (−0.20; 0.02) 0.05 (−0.07; 0.16) 0.13 (0.24;0.01) 0.20 (0.31;0.09) 0.12 (0.24;0.01)
Cerebral white mattera −0.03 (−0.07; 0.01) 0.05 (−0.06; 0.15) 0.13 (0.02; 0.23) 0.15 (0.26;0.05) 0.14 (0.25;0.04) 0.02 (−0.08; 0.13)
Cerebellar gray matterb −0.01 (−0.04; 0.02) 0.02 (−0.04; 0.10) −0.01 (−0.09; 0.07) 0.00 (−0.08; 0.08) 0.03 (−0.05; 0.11) 0.00 (−0.08; 0.08)
Cerebellar white matterb −0.01 (−0.04; 0.01) 0.03 (−0.04; 0.10) 0.04 (−0.04; 0.11) −0.02 (−0.09; 0.05) 0.01 (−0.06; 0.08) 0.06 (−0.02; 0.13)
White matter lesions 0.04 (0.02; 0.07) 0.04 (−0.02; 0.10) 0.00 (−0.07; 0.07) 0.04 (−0.03; 0.10) 0.06 (−0.01; 0.13) 0.01 (−0.05; 0.07)

Values represent standardized differences in spiral-drawing characteristics per SD increase in brain volume (95% confidence interval). Adjusted for age, sex, education, and intracranial volume.

aAdditionally adjusted for cerebellar volume.

bAdditionally adjusted for cerebral volume.

Values in bold indicate significance at level p < 0.05.