| PATIENT | AGE | DATE OF INJECTION | FILLER* AND LOCATION | TIME OF ASSESSMENT POST-INJECTION | COMPLICATIONS | MANAGEMENT | OUTCOME |
|---|---|---|---|---|---|---|---|
| 1 | 54 | 10/14/2009 | 1.3mL CaHA into nasolabial folds (NLF) and malar cheeks | Day 5 | Violaceous reticulated painful patch to right cheek with pustules | Massage, clindamycin, intralesional triamcinolone acetonide (ILTAC) | Complete resolution |
| 2 | 69 | 12/14/2009 | 1ml monophasic HA to pre-jowl sulcus, lip corners, right lateral cheek | Day 2 | Violaceous reticulated painful patch to right NLF. Right upper lip pain, numbness and ecchymosis | Massage, warm compresses, patient declined treatment with hyaluronidase and prednisone | Complete resolution |
| 3 | 26 | 01/1½010 | 0.3ml CaHA to nasal dorsum | Day 4 | Violaceous reticulated patch to right nasal ala | Warm compresses, conservative management | Complete resolution |
| 4 | 65 | 06/15/2010 | 1ml monophasic HA to NLF | 2 hours | Violaceous reticulated painful patch to left NLF | Massage, hyaluronidase | Complete resolution |
| 5 | 31 | 11/16/2011 | 2ml monophasic HA to nasojugal folds | Day 5 | Violaceous reticulated painful patch to right central cheek (Figure 1, left) | Massage, warm compresses, hyaluronidase | Complete resolution (Figure 1, right) |
| 6 | 50 | 12/6/2011 | 2ml biphasic HA to NLF (no anesthetic) | 24 hours | Violaceous reticulated painful patch to left NLF and alar crease | Massage, warm compresses, hyaluronidase, prednisone | Complete resolution |
| 7 | 56 | 06/1/2012 | 1.5mLCaHA to nasal bridge and glabella | Day 4 | Violaceous reticulated painful patch to forehead (Figure 2, left) | Massage, warm compresses, nitroglycerin paste, prednisone | Complete resolution (Figure 2, right) |
| 8 | 58 | 08/1/2012 | 3mL CaHA to inferior NLF and malar cheeks, 0.5 cc monophasic HA to superior NLF | Immediate | Violaceous reticulated patch and blanching to left NLF (Figure 3, left) | Massage, warm compresses, nitroglycerin paste, hyaluronidase, prednisone, aspirin | Complete resolution (Figure 3, right) |
| 9 | 57 | 08/18/2009 | STUDY: Particulate experimental filler | Day 3 | Violaceous reticulated painful patch and edema to right upper lip and nasolabial fold | Massage, warm compresses, nitroglycerin paste, prednisone, ILTAC | Complete resolution |
| 10 | 55 | 03/15/2010 | STUDY: Particulate experimental filler | Day 3 | Violaceous reticulated painful patch to left NLF; ecchymosis to left NLF and petechiae to lip mucosa | Massage, prednisone | Complete resolution |
| 11 | 38 | 03/15/2010 | STUDY: Particulate experimental filler | Day 1 | Violaceous reticulated patch, swelling, and sluggish capillary refill to left NLF; erosion on post-injection Day 6 | Prednisone, fucidin 2% ointment to erosion | Complete resolution |
| 12 | 36 | 03/16/2010 | STUDY: Particulate experimental filler | Day 3 | Violaceous reticulated patch, swelling, and sluggish capillary refill to left nasolabial fold | Massage, prednisone | Complete resolution |
For all patie its seen in th e authors’ office the filler is reconstituted with 2% lidocaine and 20mg/mL, 1:200,000 epinephrine unless stated otherwise