Table 2. Association between Tpcn2 SNPs and diabetic traits in humans.
Fasting insulin | HOMA_IR | ||||
---|---|---|---|---|---|
SNP | Location | Unadjusted P-value (effect) | BH adjusted P-value | Unadjusted P-value (effect) | BH adjusted P-value |
rs11604251 | chr11: 68,820,429 | 0.0073 (+) | 0.0511 | 0.6643 (+) | 0.6643 |
rs7127082 | chr11: 68,822,023 | 0.02475 (−) | 0.0937 | 0.0392 (−) | 0.2415 |
rs753559 | chr11: 68,851,605 | 0.02676 (+) | 0.0937 | 0.03936 (+) | 0.2415 |
rs10736671 | chr11: 68,858,907 | 0.0038 (+) | 0.0511 | 0.05174 (−) | 0.2415 |
Only the 4 most significant SNPs (of 14) are reported. Statistics on the additional SNPs are reported in Table S1. SNPs that remain marginally significant after adjusting for multiple comparisons using the Benjamini and Hochberg FDR method (BH) are in boldface type.