Table 3. Summary statistics describing patterns of differentiation in fully sorted regions vs. all other regions in pairwise comparisons of the subspecies of M. musculus.
Subspecies | Subspecies | Chromosome type | Window typea | nb | Average size of region (bp) (SD) | Average no. of SNPs (SD) | (SD) | (SD) | (SD) | (SD) | (SD) |
---|---|---|---|---|---|---|---|---|---|---|---|
M. m. castaneus | M. m. domesticus | Autosomes | Fully sorted | 223 | 159,193 (38,840) | 15.05** (9.17) | 0.48*** (0.16) | 0.59*** (0.13) | 0.59*** (0.13) | 0.15*** (0.10) | 0.11*** (0.07) |
Autosomes | All others | 321 | 157,243 (46,855) | 19.36** (12.56) | 0.20*** (0.13) | 0.43 *** (0.10) | 0.39*** (0.11) | 0.29*** (0.09) | 0.20*** (0.09) | ||
X | Fully sorted | 5 | 175,000 (0) | 5.20 (1.92) | 0.80 (0.12) | 0.85 (0.09) | 0.85 (0.09) | 0.06 (0.06) | 0.05 (0.04) | ||
M. m. castaneus | M. m. musculus | Autosomes | Fully sorted | 317 | 172,003** (52,573) | 16.54 (10.86) | 0.47*** (0.17) | 0.60*** (0.13) | 0.60*** (0.13) | 0.20*** (0.10) | 0.07*** (0.06) |
Autosomes | All others | 287 | 154,355** (52,334) | 18.20 (12.42) | 0.19*** (0.14) | 0.42*** (0.11) | 0.38*** (0.13) | 0.28*** (0.09) | 0.21*** (0.10) | ||
X | Fully sorted | 3 | 175,000 (0) | 3.67 (1.15) | 1.00 (0.00) | 1.00 (0.00) | 1.00 (0.00) | 0.00 (0.00) | 0.00 (0.00) | ||
M. m. domesticus | M. m. musculus | Autosomes | Fully sorted | 624 | 178,766 *** (55,386) | 13.93 (9.50) | 0.57*** (0.17) | 0.66*** (0.13) | 0.66*** (0.13) | 0.12*** (0.07) | 0.08*** (0.06) |
Autosomes | All others | 234 | 140,171*** (51,005) | 14.50 (10.45) | 0.27*** (0.16) | 0.48*** (0.12) | 0.44*** (0.14) | 0.22*** (0.09) | 0.23*** (0.10) | ||
X | Fully sorted | 10 | 16,000 (24,152) | 5.50 (1.27) | 0.70 (0.18) | 0.76 (0.15) | 0.76 (0.15) | 0.07 (0.06) | 0.05 (0.06) |
P < 0.05, ** P < 10−3, *** P < 10−7 in two-sided t-tests comparing highly differentiated autosomal regions and all other autosomal regions in each pairwise comparison.
Fully sorted regions are defined as those in which: (see Materials and Methods).
Number of delimited regions.
and refer to nucleotide diversity (Nei and Li 1979) in the first and second subspecies, respectively.