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. Author manuscript; available in PMC: 2014 Oct 1.
Published in final edited form as: Ultrastruct Pathol. 2014 Jun 25;38(5):335–343. doi: 10.3109/01913123.2014.927406

FIGURE 7.

FIGURE 7

Analysis of mitochondria in vastus medialis muscle. (A) Mitochondria of the C57BL/6J mouse appear normal, with defined cristae. Some glycogen is present. (B) The mitochondria of the C57BL/6N mouse appear distressed, lacking well-defined cristae. More glycogen can be observed as compared to the BL/6J strain. (C) Mitochondria in the Ccl2−/− knockout mutant appear distressed, with no definition of the cristae. Significant amounts of glycogen can be observed within the myocyte. (D) Mitochondria of the Ccl2−/−/Cx3cr1−/− double-knockout mutant appear highly degenerate, with both loss of definition within the cristae and loss of the outer membrane. Significant amounts of glycogen can be observed within the myocyte. Scale bar = 500 nm.