TABLE 1.
Summary of results by tissue.
Mouse strain | Tissue characteristics
|
|||||||
---|---|---|---|---|---|---|---|---|
RPE
|
Muscle: vastus medialis
|
|||||||
enDNA | Mitochondrial Degeneration | Autophagosome | Glycogen | enDNA | Mitochondrial Degeneration | Autophagosome | Glycogen | |
C57/BL6J | − | − | − | + | − | − | − | + |
C57/BL6N | + | + | − | ++ | − | + | − | + |
Ccl2−/− | + | ++ | − | ++ | − | + | − | + |
Ccl2−/−/Cx3cr1−/− | + | ++ | + | +++ | − | + | − | + |
Note: − = lacking, + = present at normal quantity, ++ = moderately elevated, +++ = highly elevated.