FIG. 1.

The effects of HFD and PE on liver TG and cholesterol contents. SD rats were administered either saline or two doses of PE (50 mg/dkg/day or 150 mg/kg/day) in the HFD groups. After 8 weeks of feeding, the rats were sacrificed, serum was collected, and the liver tissues of the control, HFD, and HFD with 150 mg/kg/day PE treatment groups were used for analysis. (A) Serum ALT level. (B) Liver tissue weight. (D) HE staining of liver tissue. Liver TG (C) and cholesterol (E) contents were analyzed using commercial kits. The values are the means±the SEM from 10 animals. *p<0.05, **p<0.01 versus the relative control group. ALT: alanine transaminase; HE, hematoxylin-eosin; HFD, high-fat diet; PE, pomegranate extract; SD, Sprague–Dawley; TG, triglyceride. To see this illustration in color, the reader is referred to the web version of this article at www.liebertpub.com/ars