Table 2.

Serum Parameters

		HFD
	Con	0	50	150 (mg/kg/day)
Insulin (mU/L)	2.2±0.4	17.8±0.7a	11.4±1b	8.9±0.9b
HOMA-IR	0.4±0.07	3.0±0.18a	2.0±0.29c	1.5±0.15b
Leptin (μg/L)	1.0±0.2	6.3±0.4a	4.0±0.5b	3.7±0.4b
Adiponectin (μg/L)	95.1±3.0	20.4±4.9a	50.4±7.1d	81.7±6.5b
TG (mM)	1.4±0.1	2.5±0.1a	2.4±0.2	1.6±0.1d
Cholesterol (mM)	1.5±0.1	1.9±0.1a	1.9±0.05c	1.6±0.1d
HDL-C (mM)	0.78±0.04	0.89±0.04	0.01±0.04c	1.04±0.04c
LDL-C (mM)	0.48±0.02	0.67±0.04a	0.56±0.04d	0.54±0.03d

The values are the means±the SEM from at least 14 animals.

^ap<0.01 versus the normal control group.

^bp<0.01 versus the HFD-fed group.

^cp<0.05 versus the normal control group.

^dp<0.05 versus the HFD-fed group.

HDL-C, high-density lipoprotein cholesterol; HOMA-IR, homeostatic model assessment–insulin resistance; LDL-C, low-density lipoprotein cholesterol; TG, triglyceride.