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. Author manuscript; available in PMC: 2014 Sep 25.
Published in final edited form as: Contemp Clin Trials. 2014 Jul 3;39(1):1–8. doi: 10.1016/j.cct.2014.06.016

Table 1.

Patient reported outcomes (PRO) measures. Patients are asked to complete a series of survey instruments that assess multiple dimensions of their quality of life and functional status at several time points throughout the trial. The surveys are administered during the initial visit, 2 weeks after the first return visit, and at 2 weeks, 4 months and 10 months after the second return visit. Abbreviations: Generalized Anxiety Disorder 7-item instrument (GAD-7); Patient Health 9-item Questionnaire (PHQ-9); Feelings About genomiC Testing Results (FACToR); Veterans RAND 12-item (VR12); Multidimensional Impact of Cancer Risk Assessment (MICRA); Big Five Inventory short 10-item questionnaire (BFI-10).

Measure Number of
items
Symptoms
Anxiety symptoms GAD-7 [32] 7
Depressive symptoms PHQ-9 [33] 9
Perceptions
Genetic test results FACToR (adapted from MICRA) [36] 26
General quality of life VR-12 + 3 [37] 15
Personality BFI-10 [56] 10