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. Author manuscript; available in PMC: 2015 Nov 1.
Published in final edited form as: Prostate. 2014 Aug 29;74(15):1506–1520. doi: 10.1002/pros.22868

Figure 6. A single or multiple rounds of castration and hormonal regeneration eliminated the ApccKO cell population.

Figure 6

(a) Timeline of tamoxifen treatment, castration, and testosterone treatment for the Regenerated group. (b) Anterior prostate lobes from regenerated and non-castrated mice. (c) Confocal mT/mG imaging for Cas-Tam mice, as well as H&E and β-catenin and Ki67 immunostaining of prostate tissues from Apcflox and ApccKO mice in the Regenerated group. (d) Diagram of the timeline of tamoxifen treatment, castration, and testosterone treatment for the Cyclic group. (e) Confocal mT/mG imaging for Cas-Tam mice, as well as H&E and β-catenin and Ki67 immunostaining of prostate tissues from Apcflox and ApccKO mice in the Cyclic group.