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. Author manuscript; available in PMC: 2015 Aug 16.
Published in final edited form as: Am J Nephrol. 2014 Aug 16;40(2):113–122. doi: 10.1159/000365255

Figure 1.

Figure 1

Graphical representation of three-way interaction showing adjusted hazard ratios all-cause mortality (ACM) for persons using compared to those not using selected antihypertensive agents in a given week

HR_ABCs_ACM = adjusted hazard ratios (HR) for all-cause mortality (ACM) based upon exposure to renin angiotensin system antagonists, β-adrenergic blockers, and/or calcium channel blockers (ABCs)

Three-way interaction terms include 1) exposed compared to not exposed to selected antihypertensive in a given week, 2) proportion of prior weeks exposed (cumulative exposure %), and 3) number of switches between exposed and not exposed weeks.

Red depicts higher hazard ratios (> 1.0) while blue depicts lower hazard ratios (< 1.0).