Table 1.
Patients characteristic and the expression of intgerin αvβ6 and transcriptional factor Ets-1
| Factor | N | αvβ6 | P | Ets-1 | P | ||||
|---|---|---|---|---|---|---|---|---|---|
| Negative | Low | High | Negative | Low | High | ||||
| Age | |||||||||
| <60 Y | 62 | 34 | 16 | 12 | 27 | 23 | 12 | ||
| >60 Y | 96 | 67 | 14 | 15 | 0.127 | 40 | 36 | 20 | 0.964 |
| Gender | |||||||||
| Male | 115 | 75 | 20 | 20 | 49 | 43 | 23 | ||
| Female | 43 | 26 | 10 | 7 | 0.705 | 18 | 16 | 9 | 0.991 |
| Location | |||||||||
| Colon | 127 | 83 | 24 | 20 | 55 | 48 | 24 | ||
| Rectum | 31 | 18 | 6 | 7 | 0.641 | 12 | 11 | 8 | 0.688 |
| Tumor size | |||||||||
| <2 cm | 15 | 9 | 4 | 2 | 6 | 6 | 3 | ||
| 2 ~ 5 cm | 109 | 70 | 22 | 17 | 47 | 40 | 22 | ||
| >5 cm | 34 | 22 | 4 | 8 | 0.624 | 14 | 13 | 7 | 0.999 |
| Differentiation | |||||||||
| Well | 28 | 22 | 4 | 2 | 15 | 9 | 4 | ||
| Moderate | 93 | 67 | 16 | 10 | 41 | 37 | 15 | ||
| Poor | 27 | 11 | 8 | 8 | 10 | 10 | 7 | ||
| Unknown | 10 | 1 | 2 | 7 | 0.000 | 1 | 3 | 6 | 0.035 |
| Duke’s phase | |||||||||
| A + B | 92 | 59 | 20 | 13 | 40 | 34 | 18 | ||
| C + D | 66 | 42 | 10 | 14 | 0.366 | 27 | 25 | 14 | 0.942 |
| T stage | |||||||||
| T1 | 48 | 31 | 8 | 9 | 19 | 18 | 11 | ||
| T2 | 70 | 42 | 16 | 12 | 28 | 30 | 12 | ||
| T3 | 33 | 24 | 4 | 5 | 18 | 9 | 6 | ||
| T4 | 7 | 4 | 2 | 1 | 0.851 | 2 | 2 | 3 | 0.470 |
| N stage | |||||||||
| N0 | 68 | 56 | 6 | 6 | 39 | 21 | 8 | ||
| N1 | 67 | 33 | 18 | 16 | 22 | 28 | 17 | ||
| N2 | 23 | 12 | 6 | 5 | 0.001 | 6 | 10 | 7 | 0.015 |
| M stage | |||||||||
| M0 | 130 | 93 | 24 | 13 | 60 | 52 | 18 | ||
| M1 | 28 | 8 | 6 | 14 | 0.000 | 7 | 7 | 14 | 0.000 |
| TNM stage | |||||||||
| I&II | 66 | 56 | 5 | 5 | 32 | 23 | 11 | ||
| III | 64 | 37 | 19 | 8 | 28 | 29 | 7 | ||
| IV | 28 | 8 | 6 | 14 | 0.000 | 7 | 7 | 14 | 0.000 |
| Histopathological type | |||||||||
| Tubular adenocarcinoma | 134 | 85 | 26 | 23 | 58 | 52 | 24 | ||
| Mucinous adenocarcinoma | 15 | 10 | 2 | 3 | 6 | 4 | 5 | ||
| Other type | 9 | 6 | 2 | 1 | 0.955 | 3 | 3 | 3 | 0.826 |