FIGURE 10.

Structural differences between hβ₂m and ΔΝ6 in the aptamer binding surface. A, the aromatic residues located in the interface between 2′F B6min and hβ₂m (see Fig. 8) are highlighted as sticks on hβ₂m (black ribbon) and ΔΝ6 (red ribbon). Close ups of four residues are shown alongside. B, the structure of hβ₂m (left) and ΔΝ6 (right) shown as a surface representation colored by its electrostatic potential (blue, positive; red, negative). The N-terminal region is highlighted in a circle, and the DE loop region is annotated with a black arc.