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Characterization of the spin-labeled GU-Aβ42 oligomers. A, a stick model of spin label R1 (PDB ID: 2Q9E). B, transmission electron microscopy images of representative spin-labeled GU-Aβ42 oligomers show globular structures with similar diameters as the wild-type oligomers. Arrows point to several of the oligomers. C, SDS-PAGE analysis of spin-labeled GU-Aβ42 oligomers. Note that overall spin labeling did not disrupt the formation of tetramers and hexamers.
