. Author manuscript; available in PMC: 2014 Sep 26.

Published in final edited form as: Curr Opin Oncol. 2011 Sep;23(5):482–487. doi: 10.1097/CCO.0b013e3283499c37

Table 2. Standardized Incidence Ratios (SIRs) of cancers in persons with AIDS in the HAART era (1996-2002) (original – references embedded).

Cancer	Standardized Incidence Ratio (95% CI)³	Viral association (%)
Kaposi sarcoma	3640 (3330–3980)	KSHV (100%)
CNS NHL	1020 (838-1220)	EBV (100%)
Non-Hodgkin lymphoma	22.6 (20.8–24.6)	EBV (varies by subtype) KSHV (varies by subtype)
Diffuse large B-cell NHL	29.6 (26.1-33.3)	EBV (30% ABC⁷, 90% IB⁴)
Hodgkin Lymphoma	13.6 (10.6-17.1)	EBV (∼90% in HIV)⁵

The SIRs represent the ratio of observed to expected new cases of cancer; the expected number is based on the age-specific rates for all of US population. Note that this is limited to AIDS cases and not inclusive of persons with non-AIDS HIV and cancer. Rates of tumor association with virus presented in the third column. AIDS = acquired immune deficiency syndrome. CI = confidence interval; EBV = Epstein Barr virus; KSHV = Kaposi sarcoma herpes virus; NHL = non-Hodgkin lymphoma.