. 2014 Oct 1;12(8):422–429. doi: 10.1089/met.2014.0050

Table 2.

Adjusted Spearman Correlations of Lipids and NMR Lipoprotein Subclass and Size Parameters with Different Measures of Insulin Resistance

	HOMA-IR in MESA^a	GDR in MUSC^b
TGs	0.36	−0.47
HDL-C	−0.39	0.22
TGs/HDL-C ratio	0.41	−0.44
Large VLDL-P	0.45	−0.39
VLDL size	0.40	−0.42
Small LDL-P	0.35	−0.50
LDL size	−0.33	0.41
Large HDL-P	−0.40	0.47
HDL size	−0.36	0.34
LP-IR score	0.51	−0.53

Spearman correlations adjusted for age, sex and ethnicity (all P<0.001).

^{^a}

Correlations with HOMA-IR in 4972 participants in the Multi-Ethnic Study of Atherosclerosis (MESA).

^{^b}

Correlations with glucose disposal rate (GDR) measured during a hyperinsulinemic-euglycemic clamp¹⁶ in 148 subjects at the Medical University of South Carolina (MUSC) (46 with untreated T2DM) (P<0.01 for HDL-C).

NMR, nuclear magnetic resonance; HOMA-IR, homeostasis model assessment for insulin resistance; MESA, Multi-Ethnic Study of Atherosclerosis; MUSC, Medical University of South Carolina; GDR, glucose disposal rate; TGs, triglycerides; HDL-C, high density lipoprotein cholesterol; VLDL-P, very-low-density lipoprotein particle number; LDL-P, low-density lipoprotein particle number; HDL-P, high-density lipoprotein particle number; LP-IR, Lipoprotein Insulin Resistance Index.