Table 3.
LP-IR Score Calculation Algorithm
| VLDL size (nm) | VLDL size score | Large VLDL-P (nmol/L) | Large VLDL-P score | LDL size (nm) | LDL size score | Small LDL-P (nmol/L) | Small LDL-P score | HDL size (nm) | HDL size score | Large HDL-P (μmol/L) | Large HDL-P score |
|---|---|---|---|---|---|---|---|---|---|---|---|
| <39.2 | 0 | <0.7 | 0 | <21.0 | 6 | <90 | 0 | <8.7 | 20 | <3.1 | 12 |
| 39.2–41.1 | 1 | 0.7–1.0 | 2 | 21.0 | 5 | 90–104 | 1 | 8.7 | 16 | 3.1–4.0 | 10 |
| 41.2–42.8 | 2 | 1.1–1.3 | 5 | 21.1 | 3 | 105–128 | 3 | 8.8 | 12 | 4.1–5.4 | 9 |
| 42.8–44.3 | 4 | 1.4–1.5 | 7 | 21.2 | 2 | 129–372 | 4 | 8.9 | 10 | 5.5–6.3 | 8 |
| 44.4–46.0 | 6 | 1.6–1.7 | 9 | >21.2 | 0 | 373–961 | 6 | 9.0 | 9 | 6.4–7.1 | 6 |
| 46.1–48.1 | 9 | 1.8–2.5 | 12 | >961 | 8 | 9.1–9.2 | 7 | 7.2–8.0 | 4 | ||
| 48.2–50.3 | 10 | 2.6–3.7 | 15 | 9.3 | 5 | 8.1–9.3 | 2 | ||||
| 50.4–51.6 | 11 | 3.8–5.3 | 18 | 9.4–9.5 | 4 | >9.3 | 0 | ||||
| 51.7–53.2 | 12 | 5.4–7.9 | 19 | 9.6–9.7 | 2 | ||||||
| 53.3–55.3 | 15 | >7.9 | 22 | >9.7 | 0 | ||||||
| 55.4–58.4 | 18 | ||||||||||
| 58.5–61.0 | 19 | ||||||||||
| 61.1–63.0 | 22 | ||||||||||
| 63.1–64.1 | 25 | ||||||||||
| 64.2–65.1 | 28 | ||||||||||
| >65.1 | 32 |
Shown are the weighting scores assigned to each category of NMR lipoprotein subclass or size parameter. The LP-IR score is calculated by summing the six NMR parameter scores.
LP-IR, lipoprotein insulin resistance index; VLDL-P, very-low-density lipoprotein particle number; LDL-P, low-density lipoprotein particle number; HDL-P, high-density lipoprotein particle number.