Table 4.

Spearman Correlations of Lipids and NMR Lipoprotein Parameters with Insulin Resistance Assessed by HOMA-IR in Subgroups of the MESA Population

	Men (n=2389)	Women (n=2583)	European American (n=2109)	Chinese American (n=642)	African American (n=1155)	Hispanic American (n=1066)	Untreated with lipid drugs (n=4186)	Treated with lipid drugs (n=786)
TGs	0.39	0.32	0.43	0.37	0.29	0.31	0.36	0.32
HDL-C	−0.35	−0.43	−0.43	−0.40	−0.30	−0.33	−0.39	−0.33
TGs/HDL-C ratio	0.42	0.41	0.50	0.43	0.35	0.37	0.43	0.37
Large VLDL-P	0.47	0.42	0.51	0.41	0.44	0.41	0.45	0.43
VLDL size	0.44	0.36	0.44	0.37	0.36	0.38	0.39	0.40
Small LDL-P	0.33	0.39	0.43	0.37	0.30	0.27	0.36	0.34
LDL size	−0.31	−0.35	−0.42	−0.39	−0.27	−0.26	−0.35	−0.34
Large HDL-P	−0.36	−0.44	−0.44	−0.40	−0.35	−0.30	−0.39	−0.35
HDL size	−0.30	−0.41	−0.43	−0.30	−0.34	−0.22	−0.35	−0.33
LP-IR score	0.51	0.52	0.58	0.49	0.48	0.45	0.51	0.49

Unadjusted Spearman correlations. All P<0.0001.

NMR, nuclear magnetic resonance; HOMA-IR, homeostasis model assessment for insulin resistance; MESA, Multi-Ethnic Study of Atherosclerosis; TGs, triglycerides; HDL-C, high density lipoprotein cholesterol; VLDL-P, very-low-density lipoprotein particle number; LDL-P, low-density lipoprotein particle number; HDL-P, high-density lipoprotein particle number; LP-IR, Lipoprotein Insulin Resistance Index.