Table 3.
GP, FACIT-fatigue, FACT/GOG-neurotoxicity and NPI scores for BDD-A patients
| Baseline (N = 13) | Cycle 3 (N = 12) | End of treatment (N = 10) | |||
|---|---|---|---|---|---|
| Mean (SD) | Mean (SD) | p valuea | Mean (SD) | p valueb | |
| GP (Grooved Pegboard) | |||||
| Dominant (s) | 99.5 (18.9) | 103.7 (30.5) | 0.443 | 103.0 (33.1) | 0.711 |
| Non-dominant | 94.1 (19.2) | 101.2 (22.7) | 0.221 | 94.1 (17.7) | 0.326 |
| FACIT-fatigue | 14.9 (11.0) | 16.3 (7.7) | 0.762 | 22.4 (11.2) | 0.114 |
| FACT/GOG-neurotoxicity | 5.9 (5.4) | 8.9 (6.7) | 0.113 | 10.9 (10.0) | 0.101 |
| NPI | |||||
| Intense | 1.8 (2.7) | 3.1 (3.2) | 0.438 | 4.5 (3.4) | 0.313 |
| Sharp | 1.3 (2.4) | 2.8 (3.2) | 0.313 | 2.6 (3.4) | 0.875 |
| Hot | 0.3 (0.7) | 1.4 (2.4) | 0.375 | 3.3 (3.4) | 0.125 |
| Dull | 0.8 (1.5) | 2.8 (3.6) | 0.125 | 4.2 (3.0) | 0.063 |
| Cold | 0.0 (0.0) | 0.9 (1.8) | 0.500 | 2.3 (3.3) | 0.250 |
| Sensitive | 0.1 (0.9) | 0.9 (1.5) | 0.375 | 3.2 (3.1) | 0.031* |
| Itchy | 0.0 (0.0) | 0.3 (0.5) | 0.500 | 1.6 (3.1) | 0.250 |
| Total | 4.1 (6.3) | 12.0 (14.4) | 0.406 | 21.7 (14.2) | 0.047* |
| N (%) | N (%) | p value | N (%) | p value | |
|---|---|---|---|---|---|
| FACIT-fatigue < 30 | 12 (92) | 11 (92) | 0.999 | 8 (80) | 0.980 |
| FACIT-GOG NP > 0 | 8 (62) | 9 (75) | 0.480 | 6 (60) | 0.999 |
* Statistically significant p < 0.05
ap value for evaluating changes from baseline to cycle 3
bp value for evaluating changes from baseline to end of treatment