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Spatio-temporal evolution of electrical potential, mechanical deformation, and muscle fiber strain across the human heart. During systole, the heart depolarizes rapidly from −80mV to +20mV, the muscle fibers contract and shorten up to 20% to induce ventricular ejection. During diastole, the heart repolarizes gradually from +20mV to −80mV, the muscle fibers relax and relengthen to their initial length to induce ventricular filling.
