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. 2014 Sep 11;5:4760. doi: 10.1038/ncomms5760

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Copyright © 2014, Nature Publishing Group, a division of Macmillan Publishers Limited. All Rights Reserved.

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(a) GO enrichment analysis reveals splicing targets responsive to endogenous Tra2α/Tra2β protein concentrations are enriched in particular biological processes associated with chromosome biology. (b) GO enrichment analysis showed some joint Tra2α/Tra2β-responsive exons were annotated to multiple overlapping biological processes. (c) Summary of GO and network analyses of joint Tra2α and Tra2β-dependent splicing targets. Individual segments of the pie chart show the percentage of Tra2α/Tra2β target genes directly annotated to the GO biological processes shown in part a; the percentage of Tra2α/Tra2β target genes that interact within the BioGrid database with partners known to be involved in the biological processes shown in part a; and the percentage of Tra2α/Tra2β target genes, which have unknown or unrelated functions. Full details of the BioGrid analysis are given in Supplementary Fig. 4.