Table 2.
Differentially expressed GPCRs and channels in the brains of sexually mature male eels
| Direction | Fold change | Protein description | Type |
|---|---|---|---|
| + | 1.66 | Extracellular calcium-sensing receptor-like [Oreochromis niloticus] | GPCR (Glutamate) |
| + | 2.07 | 5-hydroxytryptamine receptor 1B-like [Oryzias latipes] | GPCR (Rhodopsin) |
| + | 6.15 | G-protein coupled receptor 64-like [Maylandia zebra] | GPCR (Secretin) |
| + | 2.37 | Probable G-protein coupled receptor 125-like [Maylandia zebra] | GPCR (Secretin) |
| - | 0.64 | Probable G-protein coupled receptor 148-like [Oreochromis niloticus] | GPCR (Glutamate) |
| - | 0.50 | Metabotropic glutamate receptor 5-like [Danio rerio] | GPCR (Glutamate) |
| - | 0.59 | Metabotropic glutamate receptor 5-like [Oreochromis niloticus] | GPCR (Glutamate) |
| + | 3.20 | Sodium channel protein type 4 subunit alpha B-like [Maylandia zebra] | Channel |
| + | 1.91 | Sodium channel protein type 2 subunit alpha-like isoform 7 [Gallus gallus] | Channel |
| + | 1.60 | Voltage-dependent anion-selective channel protein 1 [Danio rerio] | Channel |
| + | 1.74 | Voltage-dependent anion-selective channel protein 2 [Salmo salar] | Channel |
| + | 1.66 | Voltage-dependent anion-selective channel protein 2 [Danio rerio] | Channel |
| + | 1.60 | Gamma-aminobutyric acid receptor subunit delta-like [Oreochromis niloticus] | Channel |
| + | 5.68 | Cyclic nucleotide-gated cation channel alpha-3-like [Danio rerio] | Channel |
| - | 0.64 | Potassium voltage-gated channel subfamily C member 2-like [Oreochromis niloticus] | Channel |
| - | 0.63 | Voltage-gated potassium channel subunit beta-1-like [Danio rerio] | Channel |
| - | 0.62 | Calcium-activated potassium channel subunit alpha-1-like [Xenopus tropicalis] | Channel |
| - | 0.50 | Sodium channel protein type 2 subunit alpha-like partial [Takifugu rubripes] | Channel |
G protein-coupled receptors (GPCRs) were assigned to families based on the GRAFS classification system [25]. Genes that have positive direction values were up-regulated in the brains of sexually mature male eels in comparison to immature males while those that are negative were down-regulated in this group. Gene descriptions are based on BLASTX hits in RefSeq proteins. A false discovery rate of 0.05 was used to identify differentially expressed genes.