TABLE I.
(A) | ||
---|---|---|
Given drug | Chemical Structure | Target |
Fluoxetine |
P28223 (5-hydroxytryptamine 2A receptor) P31645 (Sodium-dependent serotonin transporter) |
(B) | ||||
---|---|---|---|---|
Similar Drug (SIM) | Drug Chemical Structure (SIMchem) | Drug Targe (SIMtarget) | Original Use | |
1 | Citalopram SIM=0.556 |
SIMchem=0.66 |
P31645 SIMtarge=0.53 |
•Alcoholism •Depressive Disorder •Diabetic Neuropathies •Obsessive-Compulsive Disorder •Tobacco Use Disorder •Dementia |
2 | Fluvoxamine SIM=0.542 |
SIMchem=0.59 |
P31645 SIMtarge=0.53 |
•Depressive Disorder •Obsessive-Compulsive Disorder •Panic Disorder |
3 | Cyclobenzaprine SIM=0.532 |
SIMchem=0.54 |
P28223 SIMtarge=0.53 |
•Myositis •Muscle Rigidity •Pain •Spasm •Muscle Cramp •Muscle Spasticity •Tetanus |