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. Author manuscript; available in PMC: 2014 Sep 26.
Published in final edited form as: J Alzheimers Dis. 2010;20(0 2):S293–S310. doi: 10.3233/JAD-2010-100351

Fig. 2.

Fig. 2

Schematic representation of human mtDNA control region. Complete mtDNA control region is divided into the regulatory control region (RCR, located between nt 1 and 576) and the hypervariable control region (HCR, located between nt 16024 to 16569). OH , the origin of the heavy (H)-stand DNA replication; HSP, the promoter for the H-strand; LSP, the promoter for the light (L)-strand; TFAM, transcription factor A mitochondrial binding sites; CSBs, conserved sequence blocks I, II and III; TAS, termination associated sequence.