. Author manuscript; available in PMC: 2014 Sep 26.

Published in final edited form as: J Alzheimers Dis. 2010;20(0 2):S293–S310. doi: 10.3233/JAD-2010-100351

Table 4.

The percentage and the significance of mtDNA mutation distribution on the regulatory elements of RCR in the dementia versus non-dementia groups

Locus	nt span	Brains			Lymphoblastoid cell lines
		Non-D	D	p	Non-D	D	p
	1–212	3.6%	7.4%	0.0009	1.8%	4.7%	0.06
CSBII	299–315	4.0%	6.3%	0.013	3.5%	7.6%	0.03
LSP	392–445	0.4%	1.4%	0.01	1.0%	1.3%	NS

Non-demented values are combination of controls and DS; demented values are AD and DSAD. Non-D: Non-Demented, D: demented, NS: non-significant, nt: nucleotide.