Figure 6.
Atrogin-1 mRNA (a), MuRF1 mRNA (b), and MuRF1 (c) in gastrocnemius muscle of control, LPS and pair-fed (PF) rats treated with αMSH (100 μg/kg) or saline. LPS increased atrogin-1, MuRF1, and MuRF1 mRNA levels (P < 0.01), and αMSH administration prevented those increases. Data represent mean ± SEM (n = 7–10 rats). ∗∗P < 0.01 and ∗P < 0.05, LSD multiple comparison test.