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. 2014 Apr 28;61(2):119–125. doi: 10.1002/jmrs.46

Table 1.

Overview of the clinical trials that have used barrier products to decrease acute radiation-induced skin reactions

Product Control Patient numbers Scale Results Reference
Mepilex Lite Aqueous cream 24 RISRAS 30% decrease in erythema 21
Mepilex Lite Aqueous cream 74 RISRAS/RTOG 40% decrease in overall skin reaction severity 26
Mepilex Lite Mild salt washes 88 RISRAS Decrease in moist desquamation healing times from 23 to 16 days 27
Mepitel film Aqueous cream 78 RISRAS 92% decrease in overall skin reaction severity, decrease in moist desquamation from 26% to 0% 22
Cavilon no sting barrier film Sorbolene 61 RTOG Decrease in incidence on moist desquamation from 46% to 33% 28
Cavilon moisturising durable barrier cream Sorbolene 333 CTCAE v3 No difference between treatment and control arms 29

RISRAS, radiation-induced skin reaction assessment scale; RTOG, Radiation Therapy Oncology Group; CTCAE v3, common terminology criteria for adverse events version 3.