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. 2014 Oct 1;27(5):329–340. doi: 10.1089/jamp.2013.1099

Table 3.

Relative DD and FPD (%) Over Patient Flow Rate Range for Budesonide/Formoterol Easyhaler 320/9 μg/Inhalation and Symbicort Forte Turbuhaler

    Budesonide Formoterol Budesonide Formoterol
Product Flow* DD RSD DD RSD FPD RSD FPD RSD
Easyhaler developmental formulation Min 98 9.3 98 10.9 93 1.1 91 2.9
  Median 100 8.4 100 9.1 100 0.4 100 1.1
  Max 98 9.6 99 7.7 102 4.4 105 4.1
Easyhaler final formulation Min 98 8.1 98 8.9 89 7.2 90 6.8
  Median 100 8.0 100 8.7 100 3.0 100 1.3
  Max 103 9.4 102 9.7 102 5.1 101 4.1
Symbicort forte Turbuhaler Min 87 13.8 88 13.8 86 10.2 86 10.5
  Median 100 18.9 100 18.8 100 8.5 100 8.5
  Max 97 14.2 97 14.5 100 8.9 101 8.9
*

Weighted PIF rates through the EH and TH inhalers achieved by the 10th (min), 50th (median), and 90th (max) percentiles of asthmatic and COPD patients.