TABLE 2. miRNA levels in acrolein-treated endothelial cells.
miRNA | Fold change (array) | Fold change ± SE (rtPCR) | p |
---|---|---|---|
mir-493-5p | 2.61 | 1.69 ± 0.16 | 0.03 |
mir223 | 2.25 | 3.42 ± 1.16 | 0.02 |
let-7a | 1.50 | 1.42 ± 0.18 | 0.02 |
mir-565 | 0.22 | 0.13 ± 0.04 | <0.01 |
A quantitative analysis of four of the miRNAs listed in Table 1 was performed using RNA samples from additional HUVEC exposures (n ≥ 3). Listed are the levels as determined in the array experiment or by rtPCR (n ≥ 7 determinations) in the additional exposures.