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Histopathological and immunohistochemical findings. Photomicrographs of histological and immunohistochemical studies from representative diffuse alveolar damage (DAD) autopsy specimens are shown. This DAD patient had a final diagnosis of drug-induced lung disease (DILD). Expression of HSP47 was noted predominantly in fibroblasts, epithelial cells, and endothelial cells. A; hematoxylin-eosin staining. B; heat shock protein (HSP) 47. C; type I procollagen. Scale bar = 1 mm.
