Table 5. Comparison of all methods in analyses of adrenal cortex Dicer-KO data for mouse embryos at stages E15.5 and E16.5.

	E15.5		E16.5
	Rank	miRNAs	Rank	miRNAs
MixMir	2	[1]miR-34b-3p, [1]miR-34c-3p	1	[1]miR-34b-3p, [1]miR-34c-3p
	5	[2]let-7d-5p, [2]miR-202–3p	3	[2]let-7d-5p, [2]miR-202–3p
	8	[3]let-7d	16	[3]let-7d-5p
miReduce	1	[3]let-7d-5p	1	[2]let-7d-5p, [2]miR-202–3p
Sylamer	2	[3]let-7d-5p	NA
	10	[2]let-7d-5p, [2]miR-202–3p
cWords	1	[2]let-7d-5p, [2]miR-202–3p	3	[2]let-7d-5p, [2]miR-202–3p
	2	[3]let-7d-5p	9	[2]miR-107–3p
LM Bin	9	[2]let-7d-5p, [2]miR-202–3p	3	[1]miR-34b-3p, [1]miR-34c-3p
	13	[3]let-7d-5p	9	[3]miR-193a-3p

We present matches to miRNAs found to be experimentally downregulated in the Dicer-KO samples compared to WT in both E15.5 and E16.5 adrenal cortex samples, as reported by the authors. The top 20 motifs returned by each method were analyzed. Column labeled Rank gives the rank of the motif matched; miRNAs are preceded by the match position of the motif, with [2] indicating an exact seed match.